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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd14796dba9224f30a6cb6e42b924ff7549fa388a0634caf18076e879acfa68cf' 
  AND token = 'UkMREet6zxC3GMWM+S5S3obOGwhD6lkmmzdFLxZi1R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}