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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75902d333b380814eae34523d2693efad2a3a5a3fbaf552ca4e6e3d9a3ed58d0' 
  AND token = 'TcLYwLD/Mj9Z3HYLplnuuLBpPTC1s7sftu8/NfhK/bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}