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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a8bf3b6eb27a531bebcf808dc72fcc7d9670c76df03e8822f5c8b1625f09d2' 
  AND token = '6r9ion/JNhsQez8yqRXrKdXY9d+FI8YZzyRWlBjDBrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}