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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b736bb4f532dfb790cef777a1d2cd5788b08b795c5a46639da6cf517feb5efcf' 
  AND token = 'HMTmaYT9qDOwGx1U0D0l++QtqKdn0kcJNbQD6RHL+uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}