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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54dd593a048434a73c00663415996b1a87d53e4148598d193e2c71d2a9c74f3d' 
  AND token = 'IY9AZjdKsuiU2LK2+3tpbdLXFc6/PaSK2iChuzVAfv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}