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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec7dc03efb64101cd06b48bb9b0cd6c87303aad2c967a7ced963f85875c2a961' 
  AND token = 'VO3A+c8Hb/FcIv3J0JteHWdTvT+CTM3yxjyqEbmpa8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}