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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3dceb94d0f2cd12433eefa27750661fb28026b9a1bd3b59bc1398b716e89018' 
  AND token = 'bLaYHi8t9th0xutLbq7AqT2OBGeJSSj58aN7/ToynE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}