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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06f164ee944c053ed9f5fe36566f19a7fde16dc1da3fd217bd6b59fa3849d8d5' 
  AND token = 'iSGE4ZdsK1qcAohUSRCVJiw1bV72hVsry1zGUrFb7r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}