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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0933e511acba0014e9c3e31557f744a0e244e5b2e63643f34be48b738f97ee2b' 
  AND token = 'FqHeYes+QqxMXSkerG4uXnO0wh0SGmOs2Kn5axX7IIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}