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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1c072732ba557574163ad46d7606f7ff384736d5ce5d097b6917c16f106bc2' 
  AND token = 'mE+CMRWkGAla4Ij8r2sxv0hAZhg8hHlyJ+3UUHefAL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}