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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02ebbba1bffe68284867242d3959014a0a2e1e43fab2340f056b2159dbf4e7c3' 
  AND token = '0lnD+kCMUkDBYPF1G59J+5ZOFZjPGVZN8Emq2wRDle4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}