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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3036856b271b93d1e3be4df704011d8f2460353821b3b641d04033d5746d181a' 
  AND token = 'vY3zuH8Ng3IRX0gPUczUZjXrwIJB1OzzesTNP9JTJkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}