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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9cf3b6b7414850352ac03b58e4fffdae76a4f052a15c54980e44c088b0d0769' 
  AND token = 'u0mZwRGODEh9/PENDuBwZoAg4y1eyQxkPXd5QbjNh9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}