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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6750045173afb252271a17d7c2e238fa54daf1c834444511fa0c2dae331a6e6c' 
  AND token = 'mkJBXtOFpMHaYmKHl5GhgR0oCQCU1SpzgYhr5BTXSig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}