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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bfd2127f847e990d369f473154f91546d4eb00b86a68344a0fd905debb14c5' 
  AND token = 'c4NhnpvEmRYvfrRjzUWSwTdzFggA6oJ4H0pwEKkviu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}