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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e297cb8db26faf2a4d3937fb514baefe005208a5a68c610e1958d4f62ccf392' 
  AND token = 'DG4D3ktJf3tr2scYNBncvgIa9EgvreRWve8YRZfm1KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}