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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1dfa04ee9083046b0d9d37bdf9da3b7d8f27705859ff704717a61c842530be' 
  AND token = '48LrSTC817hpSkW2xpXPbN8MuiWmWLST/cA9xkn7zgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}