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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0447c58cfc23202e8aa022f02cbf515f420c2910a1abbc8b4d2b1942e982c954' 
  AND token = 'eDdvGBvKQcbCbsP2yUa0tIVQqr9O5Uy5NEJhi4wX2LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}