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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5e3321786f238c10acfc23757629ad05da834b6e28374d49de8061c3554600' 
  AND token = 'tU/1X1jfZrKEd3HccqfTyy9DxkgsUTxEtb3vWv8W2dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}