SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff180c33f656748f76f671d8be2e97f7218692e30b14da516be64237253104b2' 
  AND token = 'HQPPY2vBeY7kUqNkLpoVwAc1iuebDGlW/jfVtg5evlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}