SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757324e13c0251893d68b9004f5b460d58a7c3450b24e7c72e1c28629abfdae8' 
  AND token = 'mr95VQT2b9pScJzfE8QqLG+fgb5m5Ma2OPkl5thqLAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}