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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7389ba5eac0da4713b429eacab37e4317f8fb09c3044706d1894542f90c1f551' 
  AND token = 'K41hXoXxxcX1/I/tye+THLVudiNkS9gCsUvhB2/pojI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}