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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13f89e4e7d941b25b890d04a8555da957ee05af4b61015a1e392be27693e9643' 
  AND token = 'GfTMD1Ut8uC0gL0ReL5PVLn2+A3/BtnibnJW44RiD5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}