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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13dd33862f90cd20eaac7168b95c01663623e4e07f6b8fc4e3988ec1bbe15701' 
  AND token = 'yrG0J/s9xfz1svMcz11o1pNJeyGjH+LOrke+/JbqIXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}