SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628fae1f508d9aa7055837331b1cc43572ce716245c1f1b4bde812b3d903c403' 
  AND token = '+pV18A+lGA3ImS9QIi7/1Z76+vGOpGgd4vGvvwD8oeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}