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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a7acdf36287d4cc5c1089d9b05c843d8120459b4c3b25b947a1b69d700017c' 
  AND token = 'QyGYciPgvt0UckbAYYxg/isRVdxDNtaMXfv6+TOt3Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}