SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0fa3cb4607c6ed889c33853716fc961d1efa9298049dad6cb71c15ca49a87f1' 
  AND token = 'vx2msss5J9EWBMsinsRF2j1Bunw+uatoyEjcw1oqeR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}