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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9d85a45948629f21441aa09f44e705b716bb771e868c9b37d6098fd07d8f11' 
  AND token = 'H+2HwjybP5BIau27HX0SttAjlsjp018geHE0osqDtOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}