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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a46a7f2faacc795d5fd7517c76e8952f385e91da6c045cd371f69af8f64d6e' 
  AND token = 'c7qn2k57dQoL7aF5NK3QfYW0CnbUV8cVMNA+XrxpGqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}