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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2547328dcb8d5b3f1aeae430a40b54a659eb4cd5aa8541f7577e0a7fb4bfa630' 
  AND token = '+bRAgrSkG6O0ZWY9t1bjReptuylyDSWxBwDjy15SeF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}