SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc886ef6c5adbf91cfbb07e7f94dac4f27c36f0aa6d5013545906a8198e023bf' 
  AND token = '22YB6Ir1PP6GyqgRw23YErKaOGqwqLAACo66+TrLUfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}