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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c88231f6c0626465216c468ab8365b6c5ee1110040438791ac5139cc123a41' 
  AND token = 'ER5YHrZfqy5jKe6NTQUazCZlICGTOKrPd4p3cbvd4PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}