SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e47ec1a28c70158d1a61fde127b0bf61ddf455150784e492e79a50a8fcff0e05' 
  AND token = 'r8sZROrmwJA12UMzlG+Eusd2j0m1pCgvaKSPfVF80oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}