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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cca594e608b26f9c043647157dc052c4cbe02d2926d5ed1002394880ba0f218' 
  AND token = 'I78LAkfg1N5HJ1j2QXx4NF/faAPBXTKHdUW77NtuMew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}