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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '797d2155a28e81e6c8586816a647d927bbff3fdb3dd672c2a1b11165b1106a44' 
  AND token = 'JfQQRRIc861s/zR0FuzVS1TQjsrhh4UFDnK4mSh8mwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}