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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542b8f1bd4eaa43c8a5ed46be839bf500725cf57a485aa83d51bb9ac9319f43c' 
  AND token = 'lMd+x10vG2DcJgZ3kYMCTThnsMbqLMbGQppvETcMCXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}