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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a77ba179536dbee5bb6a24a8ba6f4142769a006d56990739476b9c2fc722c60' 
  AND token = 'P4n7nBuwwQ7cWXw5o3obS/3x+15KgiWCYLgY8XKF+ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}