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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de49cfed46944c5588bf294501b8b09d6e2e7620a38caf04c4baa4b2a1705ef6' 
  AND token = 'Op4Mb321JpUAMPyjhyU4XQx7aiZTK4XZokEy2VzRWcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}