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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2021f09e5480c8862f5ee78cd759e583467588fe4b97c6776c7af2af5912837c' 
  AND token = '5VrIAk6f1byz2Tq7guYEOPWON/3c2hAQqt335FPqO/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}