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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2408606f53aced937d9c4431df5a6c4fa53a74f7f86b720e2bc09549dbfabe67' 
  AND token = 'Bk/I4V5FLVY89k2SVV5Ook6hAj+R+xoQNP5qTCrDFaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}