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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c44d5a2454bcade52f0142671bf2b37036e89a67c320d28549c3e4a998e99a' 
  AND token = 'pHzlW7vdar8QVM1SYPUhTX57wPHg1rjYY23MLlt7y2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}