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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70af69bb726a7be46259cfbd4232984f40600a21fb59be1f2215430ffb8a1f2f' 
  AND token = 'JWEDEtUgVr2KYbyYz0nSAVy9BmTFSQMtwSVj2jlXGMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}