SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf43251a32cf2be35764ca2edc33e5a12e583d4d79590d3f18c580d9435b0ddb' 
  AND token = 'ayssM/aCNUmj0BGPHaNWVLe+KhZKtprQ6viB/HPHOBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}