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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfcf1879e633d512aece3e2b5c1c886d7cdf0c74388d58ca0a83e230f9aa0693' 
  AND token = 'ipMiYAYzR4/+0XLGZDgZh+UtGMLKzy06uLI6oXAzhyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}