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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e7e035442535f2177cd0c7a6ded6cfc3b1b7e5e5117e87892d46acdfc60d94' 
  AND token = 'fpkPkhjJo/7dVGq99b8a3YjCebOdsscDpnV7ExfNHeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}