SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f50db8d9ead1d92e77ddd2daaf4cf3912d6b1c26449cd1d2b052f613bea4493' 
  AND token = 'rMScuTl3+a1jRgbIEYwJzoL5moMK3cVeWp7SG+PovSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}