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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d732b3de79a4f6ab2957075f96250b0137a480990af21bd5a1f287514ad706' 
  AND token = 'eDMVl3Ay0kOt6q8txQJwkuHyMmkEfKrvSILS4zNeP2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}