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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e6d1c5ff9c752e2d256e84ad2c0f9f78b6b26e32ef8d32ab3a3818ff37002f' 
  AND token = 'BBtNa8dkOPz+LEoq+mH/TecCztdJkMGdwvf2wzBzluw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}