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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf788f044bc09d14c4bb41254b212e2852d78c15cfde344180ca62a5c47fc55' 
  AND token = 'y1XaQO+uOFAnAmVKshFrSsqHVB26YjFM9M6X5nOv2OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}