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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f4ed77c8d82f743d982eeb2c8affbdf6129bdc41c88882643c3d94f3fb8aa0' 
  AND token = 'E9G0IDhFelUPTGzUkIZeK6Ga1czERL7wrRly/iUXiHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}